增加的左心室终止透析体积指数与MitraClip植入后增加的不良事件有关
Masafumi Yoshikawa1, Hiroyuki Arashi1, Noriko Kikuchi1
1Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
The American journal of cardiology
|November 10, 2023
概括
较高的左心室末端透析体积指数 (LVEDVI) 与严重的额头吐的MitraClip手术后不良事件的增加有关. 这一发现凸显了LVEDVI作为这些患者不良结果的潜在预测因素.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 临床结果 临床结果
背景情况:
- 严重的 mitra 排泄会带来重大的临床挑战.
- 米特拉克利普手术提供了一种不那么侵入性的治疗选择.
- 预测MitraClip后不良事件的预测者需要进一步调查.
研究的目的:
- 为了检查左心室终端透缩体积指数 (LVEDVI) 和MitraClip植入后不良临床事件之间的关联.
- 确定潜在的LVEDVI值,以预测该患者队列的不良结果.
主要方法:
- 对123名接受MitraClip治疗的患者进行了回顾性观察研究.
- 接收器操作特征 (ROC) 曲线分析以确定LVEDVI切线.
- 在LVEDVI组之间对初级终点 (全因死亡率,心力衰竭住院) 的比较.
主要成果:
- 确定了118毫升/平方米的LVEDVI截止值.
- 与LVEDVI<118毫升/平方米 (24.6%) 患者相比,LVEDVI≥118毫升/平方米患者的不良事件发生率 (41.9%) 显著更高.
- 增加的LVEDVI仍然是不良事件的独立预测因子 (HR 2.24,p=0.01),即使经过对混因子的调整.
结论:
- 升高的LVEDVI与MitraClip植入后出现不良临床事件的风险增加有关.
- 在接受MitraClip治疗的患者中,LVEDVI可以作为一种有价值的预后标志物,用于严重的甲骨管吐.
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