基于octenidine和chlorhexidine的洗衣剂对Candida albicans和Candida auris的有效性 - - 一项比较研究
The Journal of hospital infection
|November 10, 2023
概括
消毒洗手具对Candida auris的有效性各不相同. 八胺二化物 (OCT) 洗手套在Candida auris去殖民化方面比赫西丁二甲 (CHG) 更有效.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 黄菌疫情需要有效的去殖民化策略.
- 建议使用抗菌洗手套进行全身脱殖.
- 有限的临床证据表明洗手套对C. auris的有效性.
研究的目的:
- 为了比较Candida auris与Candida albicans的化学耐受性.
- 为了评估抗菌洗手具对C. auris脱殖的疗效.
主要方法:
- 测试了两种类型的消毒洗衣剂 (赫西丁二甲酸盐和丁二化物).
- 敏感性测试遵循欧洲标准EN 13624.4.
- 实验使用了30秒接触时间的wash-mitt浸液.
主要成果:
- 与Candida albicans (≥10%) 相比,octenidine二化物 (OCT) 洗衣机在较低度 (≥1%) 中对C. auris的疗效更高.
- 赫西丁二甲酸盐 (CHG) 洗手套对C. albicans和C. auris菌株的有效性有限.
- 观察到C. auris的C. auris与OCT洗手间显著减少.
结论:
- 黄菌株比白菌株更容易受到测试的消毒剂的影响.
- 消毒洗剂的有效性各不相同,OCT与CHG相比,对C. auris表现优越.
相关概念视频
01:23Hand hygiene
3.3K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.3K
01:28Antimicrobial Effectiveness
24
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
24