弗雷明汉心血管风险评分和老龄化农村印度参与者的认知表现之间的关系:一个横截面分析
Abhishek Lingegowda Mensegere1, Jonas S Sundarakumar2, Latha Diwakar1
1Centre for Brain Research, Indian Institute of Science, Bangalore, Karnataka, India.
BMJ open
|November 10, 2023
概括
用Framingham风险评分 (FRS) 衡量的心血管风险因素,与印度农村成年人的认知表现较差有关. 针对心血管健康的干预措施对于保持老年人群的认知功能至关重要.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 印度心血管风险因素的上升对认知健康构成威胁.
- 了解心血管健康对老年人群认知的影响至关重要.
研究的目的:
- 研究由弗雷明汉风险评分 (FRS) 量化的心血管风险因素与认知表现之间的关联.
- 从印度农村地区的健康,老龄化个体中分析多个领域的认知功能.
主要方法:
- 对来自南印度农村的3609名45岁及以上健康,没有痴呆症的参与者的横截面分析.
- 用经过验证的计算机化测试电池评估认知表现,涵盖注意力,记忆,语言,执行功能和视觉空间能力.
- 用多重线性回归分析来确定FRS和认知结果之间的关系.
主要成果:
- 在所有评估的认知领域,更高的FRS分数与较差的表现显著相关.
- 在视觉注意力,分类流性,形式匹配,视觉空间跨度,阅读和句子理解,单词理解,语义关联,情节性记忆和名字-面部关联方面观察到的特定缺陷.
- 这些发现适用于多个认知领域,表明心血管风险对认知的广泛影响.
结论:
- 由FRS指出的心血管风险增加与中年和老年农村印度人的认知能力下降有关.
- 建议紧急实施药理和生活方式干预措施,以减少心血管风险.
- 这些干预措施可能有助于预防或减缓老年人的认知衰退.
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