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相关概念视频

Neuroplasticity01:01

Neuroplasticity

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Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
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The Nativist Approach01:21

The Nativist Approach

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The nativist approach to infant cognitive development proposes that infants are born with inherent knowledge structures that allow them to interpret the world almost immediately. This perspective contrasts with earlier developmental theories, such as those proposed by Jean Piaget, which emphasized a more gradual acquisition of cognitive abilities through interaction with the environment. One key concept in this approach is object permanence — the understanding that objects continue to...
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Genomic Imprinting and Inheritance02:30

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
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相关实验视频

Updated: Jul 11, 2025

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
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Published on: June 28, 2024

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母亲的营养编程塑造了大脑的格局.

Bandy Chen1, Elisa de Launoit2, Nicolas Renier2

  • 1Laboratory of Neurovascular Control of Homeostasis, Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.

Trends in endocrinology and metabolism: TEM
|November 10, 2023
PubMed
概括

孕产妇的肥胖会影响后代的大脑发育,可能导致神经问题. 营养编程提供了一种方法来减轻这些对儿童神经发育的负面影响.

关键词:
光在现场混合化光.孕产妇的肥胖症 母亲的肥胖症神经血管可塑性 神经血管可塑性营养规划中的营养规划空间转录学 空间转录学组织清除 组织清除

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Last Updated: Jul 11, 2025

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Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
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科学领域:

  • 神经科学是一个神经科学.
  • 发展生物学 发展生物学
  • 公共卫生 公共卫生

背景情况:

  • 孕产妇肥胖是一个日益严重的全球健康问题.
  • 早期暴露于肥胖引起的环境可能会改变后代的大脑发育.
  • 这些变化与神经系统疾病的风险增加有关.

研究的目的:

  • 研究母亲肥胖对后代神经发育的影响.
  • 探索营养规划作为抵消不良影响的策略.
  • 在孕产妇肥胖的背景下,确定改善后代大脑健康的潜在干预措施.

主要方法:

  • 使用动物模型来模拟母亲的肥胖和发育暴露.
  • 使用神经成像和行为评估来评估后代的大脑功能.
  • 在关键的发育窗口中分析特定的营养干预措施.

主要成果:

  • 孕产妇的肥胖导致后代大脑结构和功能发生显著变化.
  • 早期的营养干预表明对这些神经发育变化的保护作用.
  • 特定的饮食策略被认为有利于减轻与孕产妇肥胖相关的风险.

结论:

  • 孕产妇的肥胖症对后代的神经发育构成重大风险.
  • 营养规划是一种可行的策略,可以改善孕产妇肥胖的有害影响.
  • 有针对性的营养干预措施有望预防肥胖母亲后代的神经系统疾病.