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在质母细胞瘤中结合先天性和适应性免疫力;一个α-CTLA-4探索

Nicolas Camviel1, Leila Akkari1

  • 1Division of Tumour Biology and Immunology, Oncode Institute, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Trends in immunology
|November 10, 2023
PubMed
概括

质母细胞瘤免疫疗法在小鼠中的α-CTLA-4抗体 (Ab) 显示出前景. 这种治疗激活了CD4+ Th1 T细胞和微质细胞,从而产生强烈的抗瘤反应,对抗类似间细胞母细胞瘤.

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Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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