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人体体感官皮层的微刺激在运动皮层中唤起了取决于任务的空间模式反应
Natalya D Shelchkova1, John E Downey2, Charles M Greenspon3
1Committee on Computational Neuroscience, University of Chicago, Chicago, IL, USA.
Nature communications
|November 10, 2023
概括
体感皮层 (S1) 的皮层内微刺激 (ICMS) 通过直接和间接的途径激活了运动皮层 (M1). 仿生刺激减少了大脑控制的虚拟手中的干扰,增强了触觉反.
科学领域:
- 神经科学是一个神经科学.
- 发动机控制器的控制器
- 感官反是一种感官反.
背景情况:
- 初级运动 (M1) 和体感官 (S1) 皮层对于运动控制至关重要.
- 了解M1和S1之间的神经信号是必不可少的,但仍然是有限的.
研究的目的:
- 为了研究S1和M1.1的手表达之间的信号通路.
- 探索体感刺激对运动皮层活动和大脑与计算机接口的影响.
主要方法:
- 在S1中记录了三名手的参与者的M1神经元对皮层内微刺激 (ICMS) 的反应.
- 分析了M1激活的延迟,可变性和空间模式.
- 在虚拟手脑控制系统中测试了触觉反的仿生刺激.
主要成果:
- 在M1.1,S1的ICMS引起了短延迟 (单突触) 和可变 (间接) 的反应.
- 空间M1激活模式与感知到的手指感觉和特定于手指的M1神经元活动相关.
- 间接的S1-M1效应取决于上下文,根据行为任务而有所不同.
- 生物仿真刺激减少了由ICMS引起的M1活动引起的虚拟手部解码器性能中断.
结论:
- S1通过直接和间接的,取决于上下文的途径影响M1.
- 生物模拟触觉反策略可以减轻感官刺激对大脑控制系统的负面影响.
- 这项研究提供了关于感官-运动集成和先进的大脑-计算机接口设计的见解.
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