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降低CD3的调节可以识别高度的人类CD8T细胞

Genevieve T Clutton1, Ann Marie K Weideman2, Melissa A Mischell2

  • 1Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Clinical and experimental immunology
|November 11, 2023
PubMed
概括

对于抗击感染和癌症至关重要的高度CD8T细胞,可以通过测量CD3降低调节来识别. 这种简单的流式细胞计量方法与T细胞受体 (TCR) 激烈相关.

关键词:
CD8 + T 细胞 CD8 + T 细胞T细胞受体的T细胞受体.抗病毒免疫 抗病毒免疫人类 人类 人类 人类 人类 人类 人类瘤免疫学 瘤免疫学

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T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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