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动脉样硬化风险评估在人体动脉与异常的鼻长度:一个数值方法

Jinmay Kalita¹, Subham Show¹, Nirmalendu Biswas²

¹Department of Mechanical Engineering, NIT Durgapur, Durgapur, India.

Computer methods in biomechanics and biomedical engineering

|November 11, 2023

概括

阴道动脉鼻长度增加会增加中风风险. 较长的鼻尺寸促进血液流动的变化,增加动脉样硬化斑块的发展和心血管疾病的风险.

科学领域:

生物医学工程生物医学工程
心血管生理学心血管生理学
流体动力学流体动力学

背景情况:

心血管疾病,特别是中风,是全球日益严重的健康问题.
脑卒中通常是由动脉中的动脉硬化斑块引起的,特别是在常见动脉 (CCA) 分叉附近.
頸動脈鼻是內頸動脈 (ICA) 的擴張區域,影響血流調節,其尺寸變化,影響血液動力學.

研究的目的:

为了研究变化带鼻长度对血液动力学的影响.
分析动脉样硬化发展的生物机械风险因素.
了解鼻尺寸对动脉血流的局部和全球影响.

主要方法:

使用了3D计算流体动力学 (CFD) 模型.
使用用户定义函数 (UDF) 强加脉冲式流速配置文件.
Carotid sinus 长度被系统地改变以评估血液动力学变化和动脉样硬化风险参数.

主要成果:

增加的鼻腔长度将再循环区域转移到外壁 (OW) 以更大的强度.
在OW附近观察到较低的血流速度和增加的循环.
在较长的鼻腔的OW上,显著降低了x-壁切削应力 (x-WSS) 和时间平均壁切削应力 (TAWSS).

结论:

较长的阴道鼻长度与减少的WSS和改变的流动模式有关.
在较长的鼻中,较高的振荡切割指数 (OSI) 和相对停留时间 (RRT) 表明动脉样硬化风险增加.
动脉鼻长度增加是动脉样硬化斑块发展的重要危险因素.

关键词:

数学研究数字研究.动脉样硬化的斑块動脈動脈 - 頸動脈動脈脉动式的流动流动.这是一个很大的错误.

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