相关实验视频
Updated: Jul 11, 2025
07:37
An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
139
免疫性炎症性风湿性疾病的儿科患者的疫苗接种 - - EULAR/PRES更新的建议,2021年
Pothireddy Sharanya1, Vaishnavi Rani Kota2
1Department of Pediatrics, Maulana Azad Medical College (University of Delhi), 2, BSZ Marg, Delhi 110002.
Indian pediatrics
|November 11, 2023
概括
更新的欧洲指南现在为患有自身免疫和炎症疾病的儿童提供了关键的疫苗接种建议,重点关注疫苗的安全性和有效性.
科学领域:
- 儿科风湿病学 儿科风湿病学
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 针对患有自身免疫/炎症性疾病的儿科患者接种疫苗的欧洲初步指南于2011年发布.
- 成人建议在2019年进行了更新,强调了当前儿科指导的必要性.
- 在过去的十年中,关于疫苗安全性,有效性和免疫性出现了重要的新证据.
研究的目的:
- 提出更新的欧洲风湿病学协会联盟 (EULAR) /欧洲儿科风湿病学学会 (PRES) 关于在儿科自身免疫和炎症性疾病中接种疫苗的建议.
- 要突出从2011年指南的关键变化,以更容易专家理解.
- 帮助医疗保健提供者为家庭提供关于儿童疫苗接种的咨询.
主要方法:
- 对关于儿童类风湿性疾病疫苗安全性,疗效和免疫性最新科学文献的系统审查.
- 由EULAR和PRES专家建立的基于共识的方法.
- 更新证据与2011年EULAR建议的比较.
主要成果:
- 更新后的建议结合了最新的关于免疫功能低下儿科群体疫苗效果的证据.
- 关于各种疫苗的时间,类型和必要性的具体指导.
- 重点是平衡疫苗的益处与自身免疫性疾病儿童的潜在风险.
结论:
- 修订后的EULAR/PRES指南提供了基于证据的关键策略,以优化自身免疫和炎症性疾病儿童的疫苗接种.
- 这些更新的建议旨在改善这一脆弱群体对疫苗可预防疾病的保护.
- 专家可以利用这些指南,有效地为家庭提供咨询,并确保适当的免疫接种计划.
相关概念视频
01:21Rheumatic Heart Disease III: Medical Management
11
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
11
01:51Vaccinations
44.6K
Overview
44.6K
01:29Autoimmune Disorders
450
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
450
01:20Rheumatic Heart Disease IV: Nursing Management
14
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
14
01:23Rheumatic Heart Disease I: Introduction
14
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
14
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
37
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
37