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与乙醇摄入相关的血管损伤是由AT1受体和线粒体功能障碍驱动的

Wanessa M C Awata1, Juliano V Alves1, Rafael M Costa1

  • 1Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA; Center for Pediatrics Research in Obesity and Metabolism (CPROM), University of Pittsburgh, Pittsburgh, PA, USA; Department of Pharmacology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, SP, Brazil.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|November 11, 2023
PubMed
概括

过度的乙醇消费会通过激活氨酸-血管酶系统引起血管功能障碍,导致线粒体损伤和氧化应激. 洛萨坦治疗逆转了这些有害影响,为与酒精有关的心血管问题提供了潜在的治疗策略.

关键词:
乙醇 乙醇是一种线粒体中的线粒体.有反应性氧物种的反应性氧物种.血管功能障碍 血管功能障碍

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