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怀孕后的第二个三个月子宫疏散是否与增加的不良孕妇和新生儿后果相关?
Tal Margaliot Kalifa1, Hen Y Sela1, Jordanna Joseph1
1Department of Obstetrics & Gynecology, Shaare Zedek Medical Center, affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.
European journal of obstetrics, gynecology, and reproductive biology
|November 11, 2023
概括
怀孕后不久怀孕的第二个三个月子宫疏散并没有增加早产或其他不良结果的风险与第一个三个月的损失相比. 这些发现表明,后续怀孕的安全性概况类似.
科学领域:
- 生殖医学 生殖医学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 产科 产科 产科 产科 产科
背景情况:
- 子宫疏散是怀孕后流产的一个常见程序.
- 子宫疏散的时间,特别是在第二个三个月,可能会影响随后的怀孕结果.
- 仅有有限的数据可以比较第二次怀孕后不久怀孕后的孕产妇和新生儿的结果,与第一季度子宫疏散后的孕产妇的结果.
研究的目的:
- 为了比较怀孕后六个月内怀孕的孕产妇和新生儿的结果,第二个三个月的子宫疏散与第一个三个月的自发妊娠损失相比.
- 评估早产率的初级结果和母婴和新生儿的次要不良结果.
主要方法:
- 对1365名在2016年至2021年间分娩的妇女进行了回顾性分析.
- 在第二个三个月 (14-23周) 和第一个三个月 (<14周) 前的女性之间,结局的比较:子宫疏散.
- 统计分析包括单变量和多重逻辑回归模型来计算调整的几率比率 (aOR) 和95%置信区间 (CI).
主要成果:
- 在第二季度 (5.1%) 和第一季度 (5.3%) 子宫疏散组 (p=0.91) 之间没有观察到早产率的显著差异.
- 多变量分析证实,在第二季度疏散后,早产的风险没有增加[aOR 1.02 (0.53-1.94) ].
- 在其他不良的母亲或新生儿结局中没有发现差异,包括高血压疾病,胎盘并发症,分娩方式或出生体重.
结论:
- 与第一季度子宫疏散相比,在第二季度子宫疏散后不久怀孕不会增加早产或其他不良产周结果的风险.
- 这些发现表明,子宫疏散的时间不会对随后的怀孕结果产生负面影响.
- 建议进行进一步的研究,以加强这些发现,并提供更广泛的临床指导.
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