护理性放电功能障碍作为精神分裂症异常自我体验的可能基质
Rosa M Beño-Ruiz-de-la-Sierra1, Antonio Arjona-Valladares1, Marta Hernández-García2
1Psychiatry Department, School of Medicine, University of Valladolid, Valladolid, Spain.
Schizophrenia bulletin
|November 11, 2023
概括
精神分裂症患者在讲话时表现出听觉N1事件相关潜力 (ERP) 响应的改变,这表明冠状性排泄功能障碍. 这种功能障碍可能是精神分裂症中异常自我体验的基础.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知科学 认知科学
背景情况:
- 随之而来的放电机制通常会抑制自我生成的语音感知.
- 这种机制在精神分裂症中发生了变化,可能导致异常自我体验 (ASEs).
研究的目的:
- 为了调查精神分裂症中随随性排泄功能障碍.
- 探索它与异常自我体验 (ASE) 的联系.
主要方法:
- 记录的脑电图 (EEG) 与事件相关的潜能 (ERP),特别是听觉N1组件.
- 在自我生成的语音 (说话条件) 和听录制的语音 (听话条件) 中比较N1反应.
- 对ASEs,阳性和阴性症状进行管理的库存.
主要成果:
- 在对照组和精神分裂症患者的谈话条件中,N1振幅减少.
- 与对照组相比,精神分裂症患者的说话和听话条件之间的N1振幅差异较小.
- 这种差异与患者的症状严重程度 (ASEs,PANSS,BNSS) 有负相关性.
结论:
- 这一结果支持精神分裂症患者的尾随性排泄功能障碍.
- 这种功能障碍是精神分裂症中ASE的潜在神经基础.
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