在左心室辅助器件感染中的F-FDG PET/CT:深入描述和临床影响
Ana Devesa1, Eman Rashed2, Noah Moss2
1BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Mount Sinai Fuster Heart Hospital, New York, New York; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
F-FDG-PET/CT准确诊断左心室辅助装置 (LVAD) 感染,识别感染部位并指导临床管理. 这种成像技术显著影响患者的治疗决策,包括手术干预和移植清单状态.
科学领域:
- 核医学成像技术 核医学成像技术
- 心血管成像 - 心血管成像
- 传染病诊断 传染病诊断 传染病诊断
背景情况:
- 左心室辅助器 (LVAD) 感染是一个重大的临床挑战.
- 之前的研究表明F-FDG-PET/CT在诊断LVAD感染方面的潜力.
- 需要进行前性评估,以确认其诊断性能和临床影响.
研究的目的:
- 为了前性地评估F-FDG-PET/CT用于诊断和表征LVAD感染.
- 评估F-FDG-PET/CT发现对临床管理决策的影响.
- 为了将成像发现与特定的病原体和感染位置相关联.
主要方法:
- 40名疑似LVAD感染的患者和5名对照患者接受了F-FDG-PET/CT.
- 在四个LVAD组件中评估了吸收:出口部位,传动线,口袋和外流移植.
- 通过阳性培养和/或手术发现确认感染.
主要成果:
- F-FDG-PET/CT对LVAD感染的敏感性很高,100%的感染患者可视吸收.
- 最大吸收位置有所不同,口袋感染在细菌病患者中更为常见 (79%),并且与 Pseudomonas 和 S. aureus 有关.
- F-FDG-PET/CT的发现影响了83%的感染患者的临床管理,导致了诸如手术脱bridement,换和移植列表升级等干预措施.
结论:
- F-FDG-PET/CT是诊断LVAD感染的一个有价值的工具.
- 影像成像模式准确地描述了感染的程度和位置.
- PET/CT发现对患者管理有重大影响,改善治疗策略和治疗结果.
更多相关视频
11:09High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
10:02Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT
Published on: May 2, 2012
相关概念视频
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Cardiac Catheterization III: Left Heart Catheterization
Cardiomyopathy V: Interprofessional Care
Imaging Studies for Cardiovascular System V: CT
Acute Coronary Syndrome III: Diagnostic Studies
Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
