细菌对重金属的抗性与环境条件有关
Cheng-Han Michael Liu1, Hans-Uwe Dahms2, Chi-Ying Hsieh3
1Department of Biomedical Science and Environmental Biology, College of Life Science, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan, ROC; Research Center for Precision Environmental Medicine, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan, ROC; University Social Responsibility Project Team, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan, ROC.
Chemosphere
|November 11, 2023
概括
河流污染增加了细菌对重金属的抵抗力. 这项研究发现下游的耐药性更高,表明人类定居点有助于环境抗生素和重金属耐药性风险.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 污染的河流充当了表现出耐药性的细菌的水库.
- 废水排放将重金属和耐药细菌引入水生环境.
- 了解细菌耐药性模式对于管理水污染至关重要.
研究的目的:
- 评估吉山河水质和细菌对重金属的耐药性.
- 调查人类定居点,重金属污染和细菌耐药性之间的相关性.
- 为环境风险评估和管理提供数据.
主要方法:
- 在九个沿着山河的地点采样样本,在高平河合流的上游和下游.
- 使用磁盘扩散和微稀释方法对六种重金属的细菌耐药性的生物测试.
- 在上游和下游细菌种群之间比较耐药性水平.
主要成果:
- 细菌对重金属的耐药性在采样地点各不相同.
- 现场8展示了对重金属和抗菌剂具有共抗性的多药耐药细菌.
- 观察到下游重金属抗性增加的趋势,与人类定居点相关.
结论:
- 齐山河表现出显著的细菌对重金属的抵抗力,受到污染的影响.
- 人类定居点和相关的废水排放与增加的细菌耐药性有关.
- 这些发现为环境当局管理水污染和耐药性风险提供了参考.
相关概念视频
01:30Development of Antibiotic Resistance
17
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
17
01:30Other Stress Responses in Bacteria
20
Bacteria have global regulatory systems that control several types of stress mechanisms. These include Pho regulon and the heat shock response, which are essential systems for environmental adaptation, such as nutrient limitation and proteotoxic stress. The Pho regulon and the heat shock response exemplify bacterial resilience, enabling rapid adaptation to fluctuating environmental conditions.Pho RegulonBacteria require phosphorus for essential cellular processes, including nucleic acid...
20
01:23Stringent Response in E. coli
17
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
17
00:57Antibiotic Selection
54.4K
Overview
54.4K
01:18Other Unique Bacteria
19
Magnetic bacteria exhibit a directed movement called magnetotaxis, driven by structures called magnetosomes. These magnetosomes consist of chains of magnetic particles made of either magnetite (Fe₃O₄) or greigite (Fe₃S₄) and are organized in a linear conformation by a protein scaffold within invaginations of the cell membrane. The bacteria align along the north–south magnetic field lines, much like a compass needle. They are typically microaerophilic or anaerobic...
19
01:31Defense Against Bacterial Pathogens
1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K