肺上皮细胞中诱导的转录记忆促进了尼古丁暴露时的干扰素信号传递

Xiaoru Zhang1, Beatrix Bradford1, Sahdev Baweja2

  • 1Division of Environmental Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10010, USA.

PubMed
概括

之前接触会在肺细胞中产生细胞记忆. 这种尼克尔诱导的转录记忆会启动细胞,使它们更容易受到炎症的影响,当它们后来接触到烟草成分尼古丁时.