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相关概念视频

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

950
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
950
Development of Immunocompetence01:22

Development of Immunocompetence

317
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
317
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

68.6K
Overview
68.6K
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

836
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
836
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

507
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
507
Immunological Memory01:23

Immunological Memory

630
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
630

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相关实验视频

Updated: Jul 11, 2025

Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays
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Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays

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常见的变量免疫缺陷.

Allison Remiker1, Kristina Bolling2, James Verbsky3

  • 1Division of Hematology/Oncology/Blood and Marrow Transplantation, Department of Pediatrics, Medical College of Wisconsin, and Children's Wisconsin, Milwaukee, WI, USA.

The Medical clinics of North America
|November 11, 2023
PubMed
概括

常见变性免疫缺陷 (CVID) 是一种导致重复感染的初级免疫缺陷. 终身免疫球蛋白治疗对于预防CVID患者感染至关重要.

关键词:
这是一种自身免疫力.常见的可变免疫缺陷.这种情况是Hypogammaglobulinemia.主要免疫缺陷是一个主要的免疫缺陷.

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Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
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Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
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科学领域:

  • 免疫学 免疫学 免疫学
  • 遗传学 是一个遗传学.

背景情况:

  • 常见变性免疫缺陷 (CVID) 是最常见的原发性免疫缺陷.
  • 它的特点是免疫球蛋白的产生受损,导致各种临床症状.
  • 这些症状包括复发性感染,淋巴扩散,自身免疫,器官特异性疾病和癌症风险增加.

研究的目的:

  • 提供关于常见可变免疫缺陷 (CVID) 的全面概述.
  • 突出异质的临床表现和潜在的潜在遗传原因.
  • 强调免疫球蛋白治疗在治疗CVID中的重要性.

主要方法:

  • 关于CVID病因,临床特征和治疗的文献综述.
  • 综合有关诊断标准和管理策略的信息.
  • 分析遗传因素在免疫失调中的作用.

主要成果:

  • 冠状病毒感染带来了广泛的临床问题,不仅限于感染.
  • 遗传缺陷与CVID病例的很大一部分有关.
  • 终身免疫球蛋白替代疗法是抗体缺乏症的标准治疗方法.

结论:

  • 由于其复杂性,CVID管理需要采用多学科的方法.
  • 需要进一步研究CVID病因,以改善向治疗.
  • 持续的免疫球蛋白治疗显著降低了感染率,并改善了CVID患者的治疗结果.