对不同组合的氧化对抗Enterococcus faecalis的抗菌疗效的比较评估
Kavalipurapu Venkata Teja1, Krishnamchari Janani2, Kumar Chandan Srivastava3
1Department of Conservative Dentistry and Endodontics, Saveetha Dental College & Hospitals, Saveetha University, Chennai, Tamilnadu, India.
BMC oral health
|November 11, 2023
概括
与其他组合相比,氧化与生物活性玻璃相结合显示出对E. faecalis的抗菌效果优越. 这种协同效应显著降低了根通道中的细菌数量,突出了其作为有效的通道内药物的潜力.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 微生物学 微生物学
- 生物材料科学 生物材料科学
背景情况:
- 氧化是一种常见的通道内药物.
- E. faecalis 是一种在内牙感染中持久的细菌.
- 需要新的组合来增强抗菌疗效.
研究的目的:
- 为了比较氧化与各种药物对抗E. faecalis. 的协同抗菌疗效.
- 为了确定最有效的根管消毒组合.
主要方法:
- 使用了四百个人类下前.
- 标本被接种了E. faecalis. 的疫苗.
- 测试了五组:单独用氧化,以及用赫西丁,奇托,银纳米颗粒或生物活性玻璃S53P4.
- 使用培养方法进行细菌分析.
主要成果:
- 所有测试组都显示细菌数量显著减少 (p < 0.001).
- 与所有其他组合相比,氧化和生物活性玻璃S53P4的组合显示出最大的细菌减少 (p < 0.001).
结论:
- 氧化的协同组合增强了抗菌活性.
- 氧化与生物活性玻璃S53P4相结合是减少根通道中E. faecalis最有效的配方.
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