发现和同意基于事件的OCT和OCTA对青光眼进展的分析
Jo-Hsuan Wu1, Sasan Moghimi1, Takashi Nishida1
1Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California, San Diego, La Jolla, CA, USA.
Eye (London, England)
|November 11, 2023
概括
光学连贯断层扫描 (OCT) 和OCT血管扫描 (OCTA) 在检测青光眼症进展事件方面显示出有限的一致性. 虽然这两种方法都发现了比视觉现场测试更多的进步者,但OCT与视觉现场结果的一致性更好.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 对及时干预而言,检测青光眼的进展是至关重要的.
- 光学连贯断层扫描 (OCT) 和OCT血管扫描 (OCTA) 是先进的成像技术,用于评估玻璃眼的结构和血管变化.
- 基于事件的进展分析提供了一种敏感的方法来识别疾病的进展.
研究的目的:
- 为了比较OCT和OCTA在识别基于事件的青光眼进展方面的表现.
- 评估OCT,OCTA和视野 (VF) 测试之间的协议,以检测青光眼的进展.
- 评估海外和东欧地区在眼病管理中的互补作用.
主要方法:
- 对至少2年和4次OCT/OCTA成像访问的青光瘤患者的回顾性分析.
- 从视神经头部扫描 (ONH) 测量周周毛细管密度 (CD) 和视网膜神经纤维层厚度 (RNFL).
- 基于测量超过连续访问的测试-重新测试变异性的基于事件的进展的定义;使用kappa统计数据与视野进展率和仪器间一致性进行比较.
主要成果:
- 经合组织确定了22%的进步者,经合组织确定了17%的进步者;两者之间的一致性很小 (κ=0.06).
- 合并的OCT/OCTA分析发现了34%的进步者,突出了它们的互补性质.
- 海洋和海上国家和地区与视野进展相对一致 (κ=0.26),而海洋和海上国家和地区与海洋和海上国家和地区则略有一致 (κ=0.08). 在OCT和OCTA中,检测到的进步者比单独视觉场的进步者多.
结论:
- 海外和东欧国家和地区在检测基于事件的青光眼进展方面达成有限的协议.
- 与OCTA相比,OCT表现出与视野进展的更好的一致性.
- 两者都是宝贵的工具,用于检测青光眼的进展,提供独特和补充的信息,超过视觉现场测试单独.
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