关节痛患者患者报告的胀风险为类风湿性关节炎患者:它有价值吗?
Anna M P Boeren1,2, Sarah J H Khidir2, Pascal H P de Jong1
1Department of Rheumatology, Erasmus Medical Center, Rotterdam, The Netherlands.
Rheumatology (Oxford, England)
|November 12, 2023
概括
临床怀疑关节痛 (CSA) 患者报告的关节胀与亚临床炎症有关,并预测类风湿性关节炎 (RA) 的发展. 然而,MRI的发现比患者报告的单独胀更有预测性.
科学领域:
- 类风湿病学 类风湿病学
- 医疗成像医学成像
- 临床预测 临床预测
背景情况:
- 临床怀疑关节痛 (CSA) 患者患有类风湿性关节炎 (RA) 的风险很高.
- 患者报告的关节胀在CSA中很常见,但通常没有通过体检得到证实.
- 在CSA中自我报告的胀的诊断和预后价值需要进一步调查.
研究的目的:
- 评估患者报告的关节胀和通过成像检测到的CSA患者的亚临床炎症之间的关联.
- 为了确定患者报告的胀是否预测炎症性关节炎的发展,包括RA.
- 将患者报告的胀的预测值与成像发现和其他临床预测因素进行比较.
主要方法:
- 分析了来自荷兰的两个独立的CSA队列.
- 患者在基线报告手关节胀.
- 亚临床关节炎症使用MRI或超声波 (US) 进行评估.
- 收集了关于炎症性关节炎发展的随访数据.
主要成果:
- 患者报告的胀在各队伍中的CSA患者中有43-57%存在.
- 自我报告的胀与MRI (紧突炎) 和US (突炎) 上的亚临床炎症相关.
- 报告有胀的CSA患者患关节炎的发病率较高,独立于其他因素,但低于MRI发现.
结论:
- 患者报告的CSA关节胀与亚临床炎症有关.
- 自我报告的胀是CSA患者RA发展的独立风险因素.
- 通过MRI检测到的亚临床炎症比患者报告的胀更强烈地预测RA的发展.
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