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Updated: Jul 11, 2025

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
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在复发性缓解性多发性硬化症中,二甲基 fumarate 治疗会通过显著降低 T-helper 1 免疫力来改变 CSF 炎症性蛋白质特征.

Sara Hojjati1, Jan Ernerudh2, Magnus Vrethem3

  • 1Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Multiple sclerosis and related disorders
|November 12, 2023
PubMed
概括

多发性硬化症 (MS) 的二甲基烟酸 (DMF) 治疗显著降低了脑脊液 (CSF) 中的促炎蛋白质. 在CSF中,与神经退行相关的特定蛋白质可以预测治疗反应,为个性化医疗铺平道路.

关键词:
生物标志物 生物标志物二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸二甲基烟酸炎症 炎症是一种炎症.多发性硬化症是多发性硬化症.神经退行发生神经退行.接近延伸试验测试方法对治疗的反应.有针对性的蛋白质组学.

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