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Updated: Jul 11, 2025

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis
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Mettl3/Ythdf2通过控制Pyk2mRNA稳定性来调节巨细胞炎症和ROS生成

Yongjie Cai1, Ruiqing Yu1, Zhanqi Zhang1

  • 1Hospital of Stomatology, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.

Immunology letters
|November 12, 2023
PubMed
概括

通过调节Pyk2mRNA稳定性,RNA修饰N6-甲基氨酸 (m6A) 作者Mettl3减轻了炎症. Mettl3通过Ythdf2控制Pyk2的表达,影响炎症路径和反应性氧物种 (ROS) 生产.

关键词:
炎症 炎症是一种炎症.梅特尔的情况是这样的:这就是Pyk2的意义.这就是ROSOS ROS.在mRNA的稳定性上.

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