克洛洛 (Chloroflexus aurantiacus Malonyl-CoA reductase) 的动态盖子域控制了反应的发生

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Updated: Jul 11, 2025

Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins
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Published on: June 20, 2019

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Burak V Kabasakal1, Charles A R Cotton2, James W Murray3

  • 1Department of Life Sciences, Imperial College, Exhibition Road, London, SW7 2AZ, UK; Turkish Accelerator and Radiation Laboratory, Gölbaşı, 06830, Ankara, Turkiye.

Biochimie
|November 12, 2023
PubMed
概括

来自Chloroflexus aurantiacus的Malonyl-Coenzyme A降解酶 (MCR),对3基酸循环至关重要,在结构上具有重要特征. 晶体结构揭示了其双功能性质,并表明了涉及关键残留物的催化机制.

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