非结核性菌根性肺病是由Mycobacterium kiyosense,一种新物种引起的
Kotaro Yamada1, Takafumi Koyauchi1, Koshi Yokomura1
1Department of Respiratory Medicine, Respiratory Disease Center, Seirei Mikatahara General Hospital, Japan.
Internal medicine (Tokyo, Japan)
|November 12, 2023
概括
由非结核性菌根菌 (NTM) 引起的肺部疾病很常见. 全基因组测序发现了一种新物种,Mycobacterium kiyosense,在一个患有NTM肺病 (NTM-PD) 的患者身上.
科学领域:
- 肺部医学 肺部医学
- 微生物学 微生物学
- 基因组学就是基因组学.
背景情况:
- 人们越来越多地认识到非结核菌性肺病 (NTM-PD).
- 鉴定技术的进步有助于发现新的真菌细菌物种.
研究的目的:
- 为了识别从一个患有NTM-PD的患者中分离出来的未知菌根菌种.
- 报告第一个由新发现的物种,Mycobacterium kiyosense引起的NTM-PD病例.
主要方法:
- 胸部计算机断层扫描 (CT) 用于评估肺部发现.
- 传统方法用于初始的真菌细菌分离.
- 进行全基因组测序 (WGS) 进行了最终的物种识别.
主要成果:
- 胸部CT显示支气管切除和结节与NTM-PD一致.
- 传统方法无法识别分离的真菌菌.
- 据WGS鉴定,这些分离物是Mycobacterium kiyosense,这是2023年注册的一种物种.
结论:
- 这名患者被诊断为NTM-PD,由Mycobacterium kiyosense引起.
- 警等待作为管理策略开始使用.
- 这一案例凸显了先进的基因组技术在诊断罕见的NTM感染方面的重要性.
更多相关视频
10:10A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Published on: October 5, 2015
19.0K
09:02An Experimental Model to Study Tuberculosis-Malaria Coinfection upon Natural Transmission of Mycobacterium tuberculosis and Plasmodium berghei
Published on: February 17, 2014
19.9K
相关概念视频
Pulmonary Tuberculosis I
246
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
246
Pulmonary Tuberculosis II
243
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
243
Pulmonary Tuberculosis IV
144
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
144
Pulmonary Tuberculosis III
339
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
339
Pulmonary Tuberculosis V
183
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
183
Other Pulmonary Disorders
853
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
853
