尼加拉瓜莱昂的病特征,患病率和危险因素:基于人口的研究
Anna Strasma1,2, Ángel Mejía Reyes3, Aurora Aragón4
1Department of Medicine, Division of Nephrology, Duke University School of Medicine, Durham, NC, USA. anna.strasma@duke.edu.
BMC nephrology
|November 12, 2023
概括
慢性病 (CKD) 影响了尼加拉瓜8.6%的成年人. 这项研究确定了传统CKD和未知病因的CKD的风险因素,突出了针对性查的必要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 原因不明的慢性病 (CKDu) 不成比例地影响中美洲的年轻人.
- CKDu与环境因素,职业暴露和遗传易感性有关,而不是传统的风险因素,如糖尿病和高血压.
- 本研究的重点是估计尼加拉瓜的CKD患病率,并确定尼加拉瓜的风险因素.
研究的目的:
- 估计尼加拉瓜15-59岁成年人慢性病 (CKD) 的患病率.
- 确定与传统CKD和未知病因的CKD相关的风险因素.
主要方法:
- 一项评估尿液和血清中CKD标志物的调查在尼加拉瓜莱昂的1795名个人中进行.
- 参与者根据病史被分为传统的CKD和可疑的CKDu.
- 多项逻辑回归分析确定了与每个CKD类型相关的因素.
主要成果:
- 整体CKD患病率为8.6%,男性患病率是女性的两倍.
- 35%的CKD病例被怀疑是CKDu.
- 与传统CKD相关的因素包括家族病史,尿路感染和较低的社会经济地位.
- CKDu与饮用井水和较低的体重指数有关,同时男性性别和两种类型的年龄增加.
结论:
- 传统CKD和CKDu都在该地区构成重大公共卫生挑战.
- 这些发现支持了关于CKDu病因学的现有假设.
- 强调需要在受影响人群中广泛进行CKD查.
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