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由中药注射引起的伪过敏反应:一篇综述

Fanmei Zou^1,2, Qiuzheng Du^1,2, Yuanyuan Zhang^1,2

¹Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan Zhengzhou, China.

Chinese medicine

|November 12, 2023

概括

传统中医注射 (TCMI) 可以引起伪过敏反应. 本综述总结了它们的原因,机制和研究模型,有助于预防TCM不良事件的风险.

科学领域:

药理学药理学是指药理学的学科.
免疫学免疫学免疫学
传统中国医药传统中国医药

背景情况:

传统中医注射 (TCMI) 对于重症监护至关重要,但与不良事件有关.
伪过敏反应是显著的,发生在没有免疫球蛋白E调解的情况下,特别是初始剂量.

研究的目的:

综合审查TCMI诱导的伪过敏反应的原因和机制.
探索现有的研究模型来评估这些反应.
概述TCM伪过敏研究和风险管理的未来挑战和方向.

主要方法:

文献综述总结了导致伪过敏反应的成分和结构.
分析拟议的机制,包括巨细胞刺激和补体激活.
在伪过敏研究中使用的动物和细胞模型的审查.

主要成果:

在TCMI中确定了与伪过敏反应相关的特定组件和结构.
详细的机制涉及直接杆细胞激活和补充系统参与.
编制了各种动物和细胞模型,用于研究TCMI诱导的伪过敏.

结论:

了解TCMI伪过敏需要进一步研究致病剂和机制.
需要标准化的评估模型和指导方针来确保TCM的安全性.
本综述为TCM治疗中的风险评估和不良反应预防提供了洞察力.

关键词:

过敏原成分过敏原成分材料基础材料基础机理机制机理机制伪过敏反应伪过敏反应传统中国医学的注射.

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