VEuPathDB:在2023年成为真核病原体,载体和宿主生物信息学资源中心
Jorge Alvarez-Jarreta1, Beatrice Amos2, Cristina Aurrecoechea3
1European Bioinformatics Institute, Hinxton CB10 1SD, UK.
Nucleic acids research
|November 12, 2023
概括
简介:真核病原体,载体和宿主信息资源 (VEuPathDB) 提供了对600多种生物体的奥米克数据的访问. 它通过先进的数据挖掘和分析工具支持对真核病原体,载体和宿主的研究.
科学领域:
- 生物信息学是一种生物信息学.
- 计算生物学 计算生物学
- 病原体基因组学 病原体基因组学
背景情况:
- VEuPathDB是一个主要的生物信息学资源中心,支持对真核病原体,载体和宿主的研究.
- 自2004年以来,它一直在分析公共omics数据,整合各种数据集和分析工具.
研究的目的:
- 描述VEuPathDB资源及其最近的更新和增强.
- 通过数据挖掘和比较分析,突出其支持假设驱动研究的能力.
主要方法:
- 使用当代生物信息学工作流程对omics数据的分析,包括正统学预测 (OrthoMCL).
- 整合分析结果与数据挖掘平台,可视化工具和高级搜索功能.
- 为大规模私人数据集分析提供Galaxy工作空间和用于空间数据探索的MapVEu工具.
主要成果:
- VEuPathDB支持超过600种生物,包括无脊椎动物载体,真核病原体 (原生菌,真菌) 和宿主.
- 该平台提供超过3000个预先分析的数据集,促进跨数据集,跨数据类型和跨生物体的比较.
- 新的数据类型,搜索,功能,改进的Galaxy工作空间和重新设计的MapVEu界面已经实现.
结论:
- VEuPathDB是一个有价值的,不断发展的资源,用于探索与真核病原体,载体和宿主相关的奥米克数据.
- 最近的更新提高了它处理不断增长的OMIC数据的能力,并支持该领域的先进研究.
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