相关实验视频
Updated: Jul 11, 2025

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Characterizing Extracellular Vesicles from Biological Fluids
Published on: February 28, 2025
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囊泡百科2024:一个细胞外囊泡和细胞外粒子存储库
Sai V Chitti1, Sriram Gummadi1, Taeyoung Kang1
1Department of Biochemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
Nucleic acids research
|November 12, 2023
概括
Vesiclepedia是一个免费的数据库,列出了在细胞外囊泡 (EV) 和粒子 (EP) 中发现的DNA,RNA,蛋白质和脂质等分子. 它汇总了来自众多研究的数据,以帮助研究这些关键的生物成分.
科学领域:
- 细胞生物学 细胞生物学
- 分子生物学分子生物学
- 生物化学 生物化学
背景情况:
- 细胞外囊泡 (EVs) 和细胞外颗粒 (EPs) 是细胞分泌的,含有各种生物分子.
- 这些囊泡和颗粒涉及至关重要的生物功能.
- 关于EV和EP组成的现有数据在众多研究中分散.
研究的目的:
- 在EV和EP中创建一个全面,集中和可访问的分子载荷汇编.
- 通过提供与EV和EP相关的DNA,RNA,蛋白质,脂质和代谢物数据的统一资源来促进研究.
- 通过精心策划的数据聚合,支持对细胞外囊泡和粒子生物学的研究.
主要方法:
- 基于Web的数据聚合和策划,来自已发表和未发表的研究.
- 包括在EV和EP中检测到的蛋白质,DNA,RNA,脂质和代谢物的数据.
- 开发一个用户友好的平台 (Vesiclepedia) 来访问和检索数据.
主要成果:
- 目前,Vesiclepedia收藏了3533项EV研究的数据.
- 该汇编包含超过5万个RNA,566,000个蛋白质,3800个脂质,192个代谢物和167个DNA条目.
- 47项EV研究的定量数据可用于62,822条条目.
- 数据可以通过基于FunRich的插件下载或访问.
结论:
- Vesiclepedia 作为研究研究细胞外囊泡和粒子的研究人员的宝贵,免费资源.
- 该汇编有助于理解EV和EP的分子组成和潜在功能.
- 通过下载和插件的可访问性增强了Vesiclepedia对各种研究应用的实用性.
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