林纳,1,8-基和尤金从咖菜中转移到人类尿液中
Marcel W Debong1, Katharina N'Diaye2, Daniela Schöberl1,3
1Chair of Aroma and Smell Research, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Henkestr. 9, 91054, Erlangen, Germany.
Molecular nutrition & food research
|November 12, 2023
概括
饮食中的气味剂,如林纳醇,1,8-烯醇和尤根醇在消费后排泄到尿液中. 这项研究还发现,II期代谢物,如葡萄糖化物,通过尿液排出.
科学领域:
- 人类的新陈代谢和分泌途径.
- 饮食化合物分析和药理动力学.
背景情况:
- 了解身体如何处理和消除饮食化合物对于健康至关重要.
- 对于各种物质,排泄途径,如尿液和牛奶,可以显著不同.
研究的目的:
- 为了研究饮食中的特定气味剂在消费后通过尿液排泄.
- 为了比较尿排泄模式与以前研究的牛奶排泄模式.
- 为了分析二期代谢产物在尿液中的分泌.
主要方法:
- 哺乳期的母亲吃了一道标准化的咖菜,其中含有各种气味.
- 干预前后收集尿液样本,用于对气味物的定量分析.
- 在尿液样本上使用β-glucuronidase治疗研究了II期代谢物.
主要成果:
- 观察到林纳醇,1,8-烯醇和eugenol的尿液分泌量显著,其度在消费后1.5-2.5小时达到峰值.
- 尿液分泌模式与之前观察到的牛奶分泌模式不同.
- 在接受β-葡萄糖酶治疗后,林纳醇和尤根醇的尿度分别增加了23倍和77倍.
结论:
- 饮食摄入导致特定的气味剂 (linalool,1,8-cineole,eugenol) 转化为尿液.
- 林纳醇,尤根醇和香草的葡萄糖化物代谢物通过尿液排出.
- 饮食中的气味剂的尿排泄途径与进入牛奶的不同.
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