阴茎癌的发病率,危险因素和时间趋势:基于全球人口的研究
Junjie Huang1,2, Sze Chai Chan1, Wing Sze Pang1
1The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.
BJU international
|November 13, 2023
概括
阴茎癌的发病率在全球范围内有所不同,与酒精,艾滋病毒和不安全性行为相关的比率更高. 令人担忧的是,年轻男性的发病率正在增加,这凸显了早期检测和预防的必要性.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 阴茎癌是一个重要的全球健康问题,具有显著的地理差异.
- 了解发病率趋势和风险因素对于有效的公共卫生战略至关重要.
研究的目的:
- 分析不同年龄组的阴茎癌的全球负担和特定国家发病率趋势.
- 调查阴茎癌发生率与各种风险因素 (包括生活方式和传染病) 之间的关联.
主要方法:
- 利用了来自全球癌症观测中心,五大洲加癌症发病率,世卫组织全球健康观测中心和全球疾病负担数据库的数据.
- 雇员年龄标准化率用于发病率呈现,线性回归用于因子关联分析,并加入点回归用于趋势估计.
主要成果:
- 据估计,2020年发生了36,068例阴茎癌新病例,南美洲的发病率最高.
- 酒精消费,人类免疫缺陷病毒 (HIV) 感染和不安全的性行为与阴茎癌发病率的增加有关.
- 割礼显示出保护作用,而发病率趋势显示出整体混合模式,但年轻男性的增加令人担忧.
结论:
- 全球阴茎癌负担受酒精消费,艾滋病毒患病率,性行为和割礼率的变化影响.
- 年轻人群中的发病率上升需要迫切关注早期检测和有针对性的预防措施.
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