在中风后的次急性阶段手部自身感知和运动障碍的演变
Monika Zbytniewska-Mégret1, Christian Salzmann2, Christoph M Kanzler1,3
1Rehabilitation Engineering Laboratory, Department of Health Sciences and Technology, Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, Switzerland.
Neurorehabilitation and neural repair
|November 13, 2023
概括
在中风后,手的自知觉和运动功能的变化往往会分开. 监测两者对于在次急性阶段的个性化康复策略至关重要.
科学领域:
- 神经康复疗法 神经康复疗法
- 脑卒中恢复 脑卒中恢复的方法
- 传感器运动功能的功能.
背景情况:
- 手的自身感知对于日常活动至关重要,并且在中风后经常受到损害.
- 手部亲感的亚急性演变及其与运动恢复的关系仍然不清楚.
研究的目的:
- 为了调查手的自感和运动功能是否在中风后表现出类似的时间变化模式.
- 用机器人,临床和神经生理学方法全面量化这些变化.
主要方法:
- 通过使用机器人评估评估指部自感觉和运动功能 (力,速度,运动范围).
- 进行了临床 (例如,盒子和块测试) 和神经生理 (体感/运动唤起潜力) 评估.
- 从基线 (中风后<3个月) 追踪到4周后的变化.
主要成果:
- 42%的参与者表现出自身感应和运动功能的分离变化.
- 分离是由于基线缺乏损伤或严重的中枢通路病变 (缺席SSEP/MEP) 的结果.
- 较好的基线盒子和块测试得分与自身感知能力的增长相关.
结论:
- 在亚急性中风阶段,自身感知和运动功能经常独立变化.
- 这种分离强调了需要监测两种感觉运动模式的必要性.
- 监测可以帮助个性化中风康复疗法.
更多相关视频
相关概念视频
Spinal Cord Injury ll: Pathophysiology
Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...


