NCoR1:,mycobacterium

Kaushik Sen1,2, Viplov Kumar Biswas1,3, Arup Ghosh1,3

  • 1Immuno-genomics & Systems Biology Laboratory, Institute of Life Sciences (ILS), Bhubaneswar, Odisha, India.

Autophagy
|November 13, 2023
PubMed
概括

通过AMPK-MTOR-TFEB通路破坏自和溶酶体功能,NCOR1的枯竭会损害宿主对Mycobacterium tuberculosis (Mtb) 的防御能力. 恢复NCOR1或使用特定的治疗方法可以增强Mtb清除.

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