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在术后妄想中进行的B试验:复制研究的复制研究.

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概括
此摘要是机器生成的。

步道测试B (TMT-B) 显示了与老年人手术后妄想风险的相关性. 然而,单独的TMT-B对临床使用具有较低的预测能力.

关键词:
老年人的麻醉疗法开放科学是一个开放的科学.在外科手术期间的医学.在手术后出现的妄想症.复制复制复制复制复制复制复制风险预测风险预测步道制作试验 试验 步道制作试验

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科学领域:

  • 老年医学 老年医学
  • 神经心理学 神经心理学
  • 外科手术的结果

背景情况:

  • 步道制作测试B (TMT-B) 评估认知灵活性和相关领域.
  • 关于TMT-B和术后妄想风险的先前研究是有限的和不一致的.
  • 这项研究旨在验证术前TMT-B表现与术后妄想发病率之间的关联.

研究的目的:

  • 为了研究Trail Making Test B (TMT-B) 对老年手术患者手术后痴呆症的预测价值.
  • 为了证实或驳斥以前关于TMT-B与妄想之间的关联的发现.
  • 评估TMT-B作为术后痴呆症独立预测者的临床实用性.

主要方法:

  • 一项双国,双中心的纵向观察队列研究包括841名没有痴呆症的大型手术的老年人 (≥65岁).
  • 采集了手术前的TMT-B得分,每天两次使用验证的工具监测妄想.
  • 使用后勤回归和ROC曲线分析来评估TMT-B的预测性能,并对异常值和缺失数据进行敏感性分析.

主要成果:

  • 151名 (18%) 患者出现了术后狂妄症.
  • TMT-B评分与妄发病率有显著的相关性 (每10秒的OR增量为1.06;P=0.001).
  • 在ROC曲线下的面积为0.60 (P<0.001),表明预测性能低. 损伤或缺失的TMT-B数据也预测了妄想 (OR 2.74).

结论:

  • 追踪测试B (TMT-B) 在统计学上与术后妄想有关.
  • 然而,作为一个独立的测试,TMT-B的预测性能很低.
  • 目前,TMT-B在临床实践中不适合预测妄想.