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Updated: Jul 11, 2025

Detection of SARS-CoV-2 Receptor-Binding Domain Antibody using a HiBiT-Based Bioreporter
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探索SARS-CoV-2 RBD与haCE2结合的破坏

Camryn Carter1, Justin Airas1, Haley Gladden1

  • 1Department of Chemistry, Gottwald Center for the Sciences, University of Richmond, Richmond, VA, United States.

Frontiers in chemistry
|November 13, 2023
PubMed
概括

研究人员选了针对SARS-CoV-2受体结合域 (RBD) 和人类ACE2 (hACE2) 接口的药物. 福西诺普里尔作为一种抑制剂显示出希望,但利西尼诺普里尔形成了一个稳定的复合物,突出了需要考虑药物发现中的所有蛋白质合作伙伴的需要.

关键词:
ACE 抑制剂 是 一种 ACE 抑制剂.在 COVID-19 疫情中,在MM-GBSA中使用.这就是SARS-CoV-2病毒.人类的ACE2受体分子动力学分子动力学受体结合领域是受体结合领域.重新使用的药物.

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