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Updated: Jul 11, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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对 (+) - 甘诺辛A和 (-) - 胆固醇B的酶选择性总合成

Tomoya Mashiko1, Yuta Shingai1, Jun Sakai1

  • 1Department of Synthetic Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 142-8501, Japan.

Organic letters
|November 13, 2023
PubMed
概括

这项研究报告了首次对光学活性 (+) - 甘诺辛A和 (-) - 耳醇B的总合成. 新型合成策略实现了对这些复杂的五环天然产品的反选择性获取.

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