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在接受急性脏替代疗法治疗的COVID-19患者中,病例死亡率
Gabriel Martins Nogueira1, Paulo Novis Rocha2, Constança Margarida Sampaio Cruz1
1Escola Bahiana de Medicina e Saúde Pública, Departamento de Medicina, Salvador, BA, Brazil.
Jornal brasileiro de nefrologia
|November 13, 2023
概括
在巴西,需要急性脏替代疗法 (AKRT) 的重症COVID-19患者面临93%的非常高病例死亡率 (CFR). 大多数死亡发生在AKRT开始后的10天内,这突显了改善策略的迫切需要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 严重的COVID-19经常导致急性损伤 (AKI),这是一种与高死亡率相关的疾病.
- 关于巴西接受脏替代疗法 (KRT) 的AKI患者病例死亡率 (CFR) 的数据有限.
研究的目的:
- 为了确定在巴西接受急性脏替代疗法 (AKRT) 的重症COVID-19患者的CFR.
- 描述这些患者的特征和结果.
主要方法:
- 用AKRT治疗的COVID-19患者的回顾性描述性队列研究.
- 包括15个月内来自单一三级医院的100名患者.
- 不包括18岁以下的患者,慢性透析患者,以及COVID-19之前的AKI患者.
主要成果:
- 接受AKRT治疗的COVID-19患者的整体CFR为93%.
- 患者年龄较大 (中位数为74.5岁),经常患高血压 (76%) 和糖尿病 (56%).
- 大多数患者 (85%) 接受机械呼吸,而87%的死亡发生在AKRT开始后10天内.
结论:
- 巴西严重的COVID-19患者的急性脏替代疗法与非常高的CFR有关.
- 需要AKRT的COVID-19的老年,重症患者的预后不好.
- 对于这种患者群体,迫切需要开发改进的治疗策略.
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