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酶性甲基化作为ATP独立结合的工具

Jiaming Peng1, Gregory R Hughes2, Manuel M Müller2

  • 1Department of Chemistry, University of Basel, Mattenstrasse 24a, 4002, Basel, Switzerland.

Angewandte Chemie (International ed. in English)
|November 13, 2023
PubMed
概括

碳酸盐的酶催化F-甲基化产生了用于胺基键形成的活性. 这种新的方法使得在温和的条件下能够合成小分子,蛋白质修饰和本地化学结合.

关键词:
生物催化物的生物催化.甲基转移酶生物催化剂的生物催化原生化学结合原生化学结合后翻译修改 后翻译修改蛋白质合成 蛋白质合成

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Biological macromolecules are organic compounds, predominantly composed of carbon atoms. The carbon atoms are covalently bonded with hydrogen, oxygen, nitrogen, and other minor elements. There are four major biological macromolecule classes: carbohydrates, lipids, proteins, and nucleic acids.
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