在接受肺静脉隔离治疗的患者中,通过倾斜表测试评估巴罗受体反射的变化
Anna Zuk1, Roman Piotrowski2, Agnieszka Sikorska1
1Centre of Postgraduate Medical Education, Department of Cardiology, Grochowski Hospital, Warsaw, Poland.
概括
导管切除显著影响着巴罗受体功能,这是自主神经系统平衡的衡量标准. 与射频消除相比,冷却气球消除导致巴罗受体功能的更明显变化.
科学领域:
- 心脏病学 心脏病学
- 自主神经科学 自主神经科学
- 医疗器械 医疗器械
背景情况:
- 自主神经系统 (ANS) 是心脏功能不可或缺的一部分,并与心房 (AF) 有关.
- 对AF的导管切除 (CA) 影响自主平衡,但CA后的巴罗受体 (BR) 功能变化还未得到充分研究.
- 巴罗受体功能的评估是评估副交感活动的关键方法.
研究的目的:
- 评估导管切除 (CA) 对心房动 (AF) 患者的巴罗受体 (BR) 功能的影响.
- 为了比较射频 (RF) 与冷却气球 (CB) CA对BR功能的影响.
主要方法:
- 一项观察性前性研究包括78名患有阳性AF的患者,他们接受了他们的第一个CA.
- 患者被分为两个组:39人接受射频切除,39人接受CB切除.
- 对BR功能的非侵入性评估使用倾斜测试,测量巴罗受体事件计数 (BREC),斜率平均 (BRS) 和BR有效性指数 (BEI).
主要成果:
- 导管切除导致整个研究组中所有评估的BR功能参数 (BREC,BRS,BEI) 显著下降.
- 与射频 (RF) 组相比,冷却气球 (CB) 除组的BR功能减弱明显明显.
- 在CB组和RF组中,在BRS和BEI中观察到更大的BR功能障碍的类似趋势.
结论:
- 对心房动的导管切除显著改变了巴罗受体的功能.
- 结冷气球除与射频除相比,导致巴罗受体功能受到更大的损害.
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