远程认知训练与手机应用程序干预对精神病的影响:双盲随机对照试验
Melissa Fisher1, Kevin Etter1,2,3, Aimee Murray1
1Department of Psychiatry & Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States.
Journal of medical Internet research
|November 13, 2023
概括
这项研究表明,基于网络的认知培训计划与PRIME应用程序相结合,有效地改善了精神病患者的认知和动机. 该干预是可行的,可接受的远程交付,增强社会和职业功能.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 数字健康数字健康
背景情况:
- 认知和动机缺陷是精神病的核心,影响功能.
- 基于计算机的认知训练显示出希望,但面临着访问和坚持挑战.
- 现有有限的方法可以增强精神病治疗中的动机.
研究的目的:
- 研究基于网络的有针对性的认知和社会认知培训 (TCT) 以及精神病的PRIME应用程序的有效性.
- 评估这种远程干预的可行性和可接受性.
- 将TCT+PRIME与计算机游戏控制 (CG) +PRIME条件进行比较.
主要方法:
- 一个双盲随机对照试验,包括100名患有精神病谱系障碍的参与者.
- 远程交付30小时的TCT或CG,两者与PRIME应用程序相结合.
- 评估包括诊断面试,基线,培训后和6个月后的认知,临床和自我报告措施.
主要成果:
- 总样本显示全球认知和注意力的显著改善.
- 与CG+PRIME相比,TCT+PRIME在情绪识别方面表现出更大的收益.
- 在动机,抑郁和积极症状方面观察到显著改善.
结论:
- 远程CTCT与PRIME应用程序相结合是可行的,可以接受的,并改善认知,动机和精神病的症状.
- TCT+PRIME显示了增强情绪识别和全球认知的潜力.
- 进一步的分析将探讨参与与结果之间的关系.
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相关概念视频
Blind Procedures
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...
Blinding
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
