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对膜蛋白原生质谱的洗剂交换方法的批判性评估

Iliana Levesque1, Brock R Juliano1, Kristine F Parson1

  • 1Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.

Journal of the American Society for Mass Spectrometry
|November 13, 2023
PubMed
概括

膜蛋白 (MPs) 的洗剂交换协议通常是无效的,原始洗剂的多达99%仍然存在. 这项研究强调了需要改进的方法来准确地研究MP结构,使用本地质谱 (nMS).

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