菌体疗法:英国临床医生的认识和需求
Emily A Simpson1, Helen J Stacey2, Ross J Langley3,4
1Medical Microbiology, Ninewells Hospital, NHS Tayside, Dundee, United Kingdom.
PloS one
|November 13, 2023
概括
临床医生担心抗生素耐药性,并看到许多感染抗生素耐药的患者. 一项调查显示,人们对使用菌体 (菌体) 治疗作为替代治疗方法有很大的兴趣和意愿.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 医学研究 医学研究
背景情况:
- 抗生素耐药性对患者护理和医疗保健系统构成重大威胁.
- 对传统抗生素治疗耐药的感染的发展需要替代的抗菌策略.
- 菌体 (菌体) 疗法正在成为一种有希望的替代抗菌方法.
研究的目的:
- 评估英国临床医生的意识,感知和愿意使用菌体疗法.
- 确定跨医学专业的菌体疗法开发的临床需求和优先事项.
主要方法:
- 在两家苏格兰卫生局向各种医疗和外科专业的临床医生分发了一个匿名的10个问题调查.
- 来自26个专业的90名临床医生回应了,提供了关于他们对抗生素耐药性和菌体治疗的经验的数据.
主要成果:
- 高比例的受访者 (83/90) 在过去的一年中遇到了抗生素耐药性感染的患者.
- 超过一半 (58.8%) 曾听说过菌体疗法,其中葡萄球菌, Pseudomonas 和大肠杆菌被确定为关键目标.
- 相当多的临床医生 (77/90) 估计看到的患者可能受益于菌体疗法,71.1%表示愿意考虑使用它.
结论:
- 在英国的临床医生中,有相当大的需求和准备在适当的情况下采用菌体疗法.
- 跨专业的广泛兴趣凸显了菌体治疗的潜在临床实用性和广泛影响.
- 增加对菌体治疗的准入,可以为患者和医疗保健提供者带来显著的临床和经济优势.
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