在重症监护室治疗的COVID-19患者中 Delirium
Jae Hoon Lee1, Won Ho Han1, June Young Chun2
1Critical Care Medicine, National Cancer Center, Goyang, South Korea.
PloS one
|November 13, 2023
概括
在COVID-19患者中,妄想与老年,高血压和机械通风有关. 在重症监护室 (ICU) 识别这些危险因素可以帮助预防和治疗妄,改善患者的治疗结果.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 神经学 神经学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 可能导致急性器官功能障碍.
- 重症患者的妄想与不良结果有关,包括长时间住院和长期认知障碍.
- 了解进入重症监护室 (ICU) 的COVID-19患者 Delirium 的风险因素对于及时干预至关重要.
研究的目的:
- 为了调查与COVID-19肺炎的重症监护室 (ICU) 患者痴呆症发展相关的风险因素.
- 确定预测这种患者群体痴呆的人口统计学,临床和治疗相关因素.
主要方法:
- 回顾性单中心研究,包括111名患有COVID-19肺炎的成年患者,需要氧气治疗.
- 从电子健康记录中收集的数据包括人口统计,病史,疾病严重程度 (序列器官衰竭评估得分) 和治疗策略.
- 统计分析,包括单变量和多变量逻辑回归,被用来识别妄的重大风险因素.
主要成果:
- 统一分析确定了老年,高血压,更高的序列器官衰竭评估得分,机械呼吸器支持,神经肌肉阻断剂的使用,以及更长的ICU停留时间作为重要因素.
- 多变量分析证实了老年,高血压,机械呼吸器支持和更长的ICU停留时间作为妄想的独立预测因素.
- 特定的风险因素包括老年 (OR 1.149),高血压 (OR 8.651),机械呼吸 (OR 226.215),以及ICU停留时间 (OR 30.295).
结论:
- 高龄,高血压,需要机械通风和长时间的ICU住院是COVID-19患者妄的重要危险因素.
- 这些发现凸显了早期识别和管理 Delirium 在危急病 COVID-19 患者的战略的重要性.
- 需要采取积极的措施来预测和预防这种脆弱人群中的妄想症.
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