改善NCBI GenBank和相关数据库的黄金标准:来自类型标本和类型菌株的DNA序列
Susanne S Renner1, Mark D Scherz2, Conrad L Schoch3
1Department of Biology, Washington University, Saint Louis, MO 63130, USA.
Systematic biology
|November 13, 2023
概括
从类型标本中精选DNA序列对于准确的生物多样性识别至关重要. 虽然 prokaryotes 和真菌显示进展,更多的类型衍生DNA数据是需要的真核生物来保护生物多样性.
科学领域:
- 生物多样性信息学 生物多样性信息学
- 基因组科学 基因组科学
- 分类学 分类学是指分类学.
背景情况:
- 科学名称和链接的DNA序列对于生物多样性知识的获取和识别至关重要.
- 国家生物技术信息中心 (NCBI) 对类型衍生序列的策划对于改进基于DNA的识别至关重要.
- 类型材料是分类学识别的黄金标准.
研究的目的:
- 分析来自NCBI的命名类型材料的DNA序列的标记和修复.
- 评估不同生命形式类型衍生序列的当前状态.
- 确定提高生物多样性保护类型衍生序列可用性的策略.
主要方法:
- 在NCBI对精选的基因组组合和DNA序列的分析.
- 审查数据提交流程和策划工作.
- 对原核生物,真菌和其他真核生物的序列数据的检查.
主要成果:
- 美国国家生物研究所已经从原生类菌株中策划了18,281个基因组组.
- 超过21000种真菌有类型衍生序列,对于识别至关重要.
- 其他真核生物 (关节动物,脊椎动物,胚胎生物) 的类型衍生序列目前非常有限.
结论:
- 扩展类型衍生DNA序列,特别是对于真核生物来说,对于生物多样性的记录和保护至关重要.
- 需要增加类型标本的序列,更新元数据要求和改进数据提交实践.
- 研究人员,博物馆和数据库之间的协作努力对于增强生物多样性信息学至关重要.
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