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Updated: Jul 11, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

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免疫功能低下患者的SARS-CoV-2遗传变异水平较高:一项回顾性病例对照研究

Romane Guilbaud1, Anna-Maria Franco Yusti1, Valentin Leducq2

  • 1Infection, Antimicrobials, Modelling, Evolution, Université Paris Cité and Sorbonne Paris Nord, Inserm, Paris, France.

The Journal of infectious diseases
|November 13, 2023
PubMed
概括

严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染在免疫功能低下的个体中持续更长时间,导致病毒遗传多样性增加. 这种增加的多样性可能会导致具有改变特征的新SARS-CoV-2变种的出现.

关键词:
这就是SARS-CoV-2病毒.案例控制 - 情况控制.遗传多样性 遗传多样性基因组动力学 基因组动力学免疫功能受损的患者.

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