在一所大学的肺癌查计划中,描述肺RADS类别4病变的特征
Madison Kocher Wulfeck1, Samuel Plesner2, James E Herndon1
1Department of Radiology, Duke University Medical Center, 2301 Erwin Road Box 3808, Durham, NC 27710, USA.
Lung cancer (Amsterdam, Netherlands)
|November 13, 2023
概括
肺癌查 (LCS) 在7.6%的检查中发现肺-RADS类别4结节,其中16%证明是恶性. 肺癌的风险从类别4A到4X显著增加,成像功能有助于区分.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 肺部病理学 肺部病理学
背景情况:
- 肺癌查 (LCS) 使用肺成像报告和数据系统 (Lung-RADS) 来分类肺结节.
- 肺RADS类别4表示需要进一步调查的高风险结节.
- 在患者管理中,区分4类内良性和恶性结节对于患者管理至关重要.
研究的目的:
- 为了确定患有肺-RADS类别4结节的患者肺癌的患病率.
- 确定临床和成像特征,可以在这个高风险群体中区分良性病变和肺癌.
主要方法:
- 2018年1月至2021年12月期间LCS考试的回顾性审查.
- 包括所有患有肺RADS类别4病变的患者.
- 收集患者的人口统计数据,最近的症状和详细的成像特征.
主要成果:
- 在4819个LCS检查中,7.6%显示肺RADS类别4结节;1.2%的患者患有活检证明的肺癌.
- 恶性瘤的发病率在各个子类别中增加:4A的6.3%,4B的20.2%,4X的71.0%.
- 影像特征,如内支气管阻塞,膜结合,不规则的形状,洞穴和异质的囊性外观与恶性瘤有关. 临床症状没有显示出与肺癌的统计学意义上的关联.
结论:
- 肺RADS类别4结节存在于7.6%的LCS检查中,总体恶性瘤率为16%.
- 肺癌的概率从类别4A升至4X.
- 特定的成像特征可以帮助在肺RADS类别4分类中区分良性和恶性结节.
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