药物引起的听力损失: 倾听最新的进展
Pierre Reynard1, Hung Thai-Van1
1Service d'audiologie & explorations oto-neurologiques, hospices civils de Lyon, hôpital Edouard-Herriot & hôpital Femme Mère-Enfant, 69000 Lyon, France; Institut Pasteur, Institut de l'Audition, Center for Research and Innovation in Human Audiology, 75000 Paris, France; Université Claude Bernard Lyon 1, 69622 Villeurbanne, France.
概括
感官神经听力损失 (SNHL) 是常见的和不可逆转的. 本综述确定了导致耳毒性的药物类别,并讨论了最近的治疗和预防策略.
科学领域:
- 耳部毒理学 耳部毒理学
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 感官神经听力损失 (SNHL) 是最常见的听力损失形式,由于听觉感官细胞或神经受损.
- 内耳毛细胞缺乏再生能力,使得SNHL往往是永久的和不可逆转的.
- 耳毒性,药物引起的内耳损伤,可以影响毛细胞及其支持系统.
结论:
- 了解耳毒性机制对于开发有针对性的干预措施至关重要.
- 积极的临床策略,如风险评估和听力监测至关重要.
- 需要对较少的耳毒替代品和保护剂进行持续的研究.
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