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Updated: Jul 11, 2025

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
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基于蛋白质的带通波器,用于通过化学输入控制细胞信号

Sailan Shui1,2, Leo Scheller1,2, Bruno E Correia3,4

  • 1Laboratory of Protein Design and Immunoengineering (LPDI)-STI-EPFL, Lausanne, Switzerland.

Nature chemical biology
|November 13, 2023
PubMed
概括

研究人员设计了基于蛋白质的带通波器 (CBPs),可以控制细胞反应. 这些新型过器表现出OFF-ON-OFF模式,对特定的化学度做出反应,而忽略其他度.

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