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中国湖南省出生缺陷产周死亡率,2010-2020年

Xu Zhou¹, Donghua Xie², Jian He²

¹Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan Province, China. chzhouxu@163.com.

BMC pregnancy and childbirth

|November 14, 2023

概括

出生缺陷对围产期死亡率有很大影响. 农村位置和较低的母亲社会经济地位等因素与更高的风险有关,尽管这一比例正在下降.

科学领域:

围产期健康围产期健康
出生缺陷流行病学的流行病学
公共卫生监督是对公共卫生的监督.

背景情况:

出生缺陷是一个主要的全球健康问题,影响胎儿和新生儿的结果.
了解出生缺陷的流行病学对于开发有效的公共卫生干预措施至关重要.

研究的目的:

确定与出生缺陷相关的围产死亡率 (PMR).
确定出生缺陷与各种母体和人口因素之间的关系.

主要方法:

利用中国湖南省出生缺陷监测系统 (2010-2020) 的数据.
使用日志二项式回归计算了流行率 (PR) 和PMR,并通过千平方测试分析了趋势.
通过粗略的几率比率检查了母亲特征和围产期死亡之间的关联.

主要成果:

在1,619,376名胎儿中确定了30596例先天性缺陷,先天性缺陷占18,212例围产期死亡的42.0%.
观察到出生缺陷的PMR的下降趋势,从2010年的37.03%到2020年的21.00%.
先天性心脏缺陷和脑有较高的PMR;农村地区,女性胎儿和较低的母亲社会经济因素与风险增加有关.

结论:

出生缺陷是围产期死亡的一个重要原因,并确定了特定的风险因素.
在PMR下降趋势表明干预计划的潜在有效性.
建议对潜在机制进行进一步的研究,以帮助减少与出生缺陷相关的围产死亡.

关键词:

出生异常是先天的异常.流行病学流行病学围产期死亡围产期死亡产前死亡率产前死亡率风险风险风险风险风险

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