根据类风湿性关节炎病例的疾病活性而发生的非接触性美图学变化
Amr Mounir1, Mohamed Anbar2, Islam Awny2
1Ophthalmology Department, Sohag Faculty of Medicine, Sohag University, Almohafza St., Sohag, Sohag City, 82511, Egypt. dramrmonir@yahoo.com.
BMC ophthalmology
|November 14, 2023
概括
类风湿性关节炎 (RA) 疾病的活性,而不是持续时间,与干眼疾病 (DED) 的严重程度相关. 非接触式美图学有效量化了RA患者的DED,有助于疾病分级.
科学领域:
- 眼科医生 眼科 眼科
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 类风湿性关节炎 (RA) 是一种全身性自身免疫性疾病,可以影响眼部结构.
- 干眼病 (DED) 是RA患者常见的并发症,影响他们的生活质量.
- 在RA中对DED的客观评估对于有效管理至关重要.
研究的目的:
- 在RA患者中测量DED活性.
- 为了将DED与RA活动和持续时间相关联.
- 客观地评估DED在活跃的RA病例中的严重程度,使用非接触式meibography.
主要方法:
- 使用Scheimpflug拓仪 (Sirius) 进行红外非接触性微图,对30名RA患者进行了测试.
- 根据DAS-28问卷,患者被分为低至中度和高RA活性组.
- 评估了梅博米腺结构,眼膜非侵入性分解时间 (NI-BUT) 和梅博斯core.
主要成果:
- 较高的RA活性 (DAS-28得分) 与显著的眼睛表面变化有关,包括梅博米腺功能障碍和NI-BUT.
- 在RA活性 (DAS-28) 和各种DED参数之间发现了中等的相关性.
- 在DED和RA持续时间之间没有发现显著的相关性.
结论:
- 通过DAS-28评估的RA疾病活性与RA患者的DED参数有中等的相关性.
- 无接触式微图学是评估和分类RA中的DED的宝贵工具.
- 来自meibography的Meiboscore和Meiboscale有助于在不同RA活动级别中对DED进行分级.
相关概念视频
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
37
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
37
Myocarditis II: Clinical Features and Diagnostic Tests
12
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
12


