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相关概念视频

Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

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Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs but also impacts other areas, such as the arms, thereby impairing overall circulation and organ function.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty deposits inside the arterial...
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Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

10
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
10
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

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 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
11
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

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Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
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Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

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Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
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甲状腺疾病和周围动脉疾病

Katica Bajuk Studen1,2, Simona Gaberscek1,2, Katja Zaletel1,2

  • 1Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Current vascular pharmacology
|November 14, 2023
PubMed
概括

甲状腺功能障碍,包括甲状腺功能障碍和甲状腺功能障碍,会增加心血管疾病的风险. 研究探讨了甲状腺疾病和外周动脉疾病之间的联系,突出了潜在的机制,如内皮功能障碍和炎症.

关键词:
甲状腺功能低下症 甲状腺功能低下症在此基础上,我们进行了以太基因生成.脱脂血症是什么情况它们的内皮质 (endothelium).这种高血压,高血压.甲状腺功能过强症 甲状腺功能过强症这是一种炎症,炎症.

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科学领域:

  • 内分泌学 在内分泌学.
  • 心血管医学 心血管医学
  • 血管生物学 血管生物学

背景情况:

  • 甲状腺疾病 (甲状腺功能低下,甲状腺功能过高) 与心血管疾病 (CVD) 风险有关.
  • 甲状腺刺激激素 (TSH) 水平显示出与心血管风险的U形关联.
  • 连接甲状腺功能和心血管疾病的机制已知,但外围动脉疾病 (PAD) 的并发症需要进一步调查.

研究的目的:

  • 在患有甲状腺功能障碍的患者中调查周围动脉疾病 (PAD) 的特定临床并发症.
  • 探索将甲状腺功能低下症和甲状腺功能过高症与PAD联系起来的病理生理机制.

主要方法:

  • 对甲状腺功能和心血管风险的流行病学研究和元分析的审查.
  • 对 hypothyroidism-PAD 和 hyperthyroidism-PAD 提出的病理生理路径的分析.

主要成果:

  • 甲状腺功能障碍和甲状腺功能障碍都与心血管疾病和死亡率的增加有关.
  • 甲状腺功能低下-PAD的潜在机制包括内皮功能障碍,血压变化,脂质不良和炎症.
  • 甲状腺功能增高-PAD的潜在机制包括高动态循环,高静脉血压,高凝固性和动脉炎症.

结论:

  • 甲状腺功能障碍对心血管并发症构成重大风险,包括外围动脉疾病.
  • 了解具体机制对于在甲状腺患者中开发针对PAD的临床干预措施至关重要.
  • 需要进一步的临床试验以PAD终点为重点,以充分调查这些关联.