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腹腔大动脉动脉硬性斑块指数可以预测机器人辅助部分切除术后的功能结果吗?

Alessandro Veccia¹, Emanuele Serafin¹, Alessandro Tafuri^1,2

¹Department of Urology, Azienda Ospedaliera Universitaria Integrata Verona, 37126 Verona, Italy.

Diagnostics (Basel, Switzerland)

|November 14, 2023

概括

腹腔大动脉动脉硬化斑块指数 (API) 预测慢性病 (CKD) 后机器人辅助部分切除术 (RAPN) 癌. 较高的API值表明CKD风险增加,有助于个性化治疗策略.

科学领域:

腎臟病學 (nephrology) 是一種醫學.
心血管外科心血管外科
在瘤学瘤学.

背景情况:

机器人辅助部分切除术 (RAPN) 是对细胞癌 (RCC) 的标准治疗方法.
慢性病 (CKD) 是RAPN后的一个潜在并发症.
术后CKD的预测标记对于患者管理至关重要.

研究的目的:

调查腹腔大动脉动脉硬性斑块指数 (API) 在RCC患者的RAPN后对CKD发展的预测价值.
评估API与手术前或手术后CKD发生率之间的关联.

主要方法:

对183名接受RAPN治疗RCC的患者进行了回顾性分析.
从CT扫描中计算的API是动脉硬性斑块体积与腹腔大动脉体积的比率.
后勤回归和ROC分析,以确定API对CKD的预测性能.

主要成果:

该药物对CKD发展有显著的影响 (系数为0.13,p=0.006).
多变量分析确定API ≥10作为术后CKD的独立预测因子 (OR 25.4,p=0.01).
在第二个模型 (OR 25.2,p=0.04) 中,API ≥10是与CKD发展相关的唯一因素.

结论:

腹腔大动脉动脉硬化斑块指数 (API) 是术后CKD的强有力的预测指标,用于治疗RCC的RAPN患者.
API评估可以帮助外科医生识别高风险患者并定制治疗策略.
使用API可能会改善患者的治疗结果,并在RCC治疗中提供个性化的护理.

关键词:

腹部大动脉斑块动脉样硬化指数慢性脏疾病慢性脏疾病机器人辅助部分切除术

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